CBG
introduction
Along with THC and CBD, CBG is one of the cannabinoids that can be found in hemp. Cannabigrol, as the drug is called, is getting more and more attention in the news. And not for nothing. Cannabis seems to work very well in the first tests. So let’s take a look at what the latest research on cannabigrol has found.
מה זה CBG?
Some types of cannabis have quite large amounts of cannabigerol. Most of the time, CBD and THC are made from CBG in the plant. But some types of cannabis are a little different. With these species, an important enzyme is not formed. And it’s this enzyme that makes sure it turns into CBD and THC, leaving a lot more CBG in the plant. Young hemp plants also have more cannabigrol than older ones.
The lesson is that if you harvest your hemp early, it will have a higher amount of CBG. Although there haven’t been many clinical studies on how CBG affects people, animal testing has given us some clues.
CBD, THC and other cannabinoids seem to work together with CBG in the cannabinoid control system. And thus make the balance of the body stronger. Like CBD, CBG is non-addictive and doesn’t make you feel high or stoned.
Cannabinoids
Cannabinoids are a group of chemicals found naturally in the cannabis plant. Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two most well-known cannabinoids.
THC is the main psychoactive ingredient in cannabis, which is what makes people feel “high” when they use it. It works by binding to cannabinoid receptors in the brain and nervous system.
CBD, however, does not make people feel high. Instead, it is believed to have many healing qualities. CBD works by working with the body’s endocannabinoid system (ECS), which controls many physical and mental processes, such as how we feel pain, how hungry we are, and how we remember things.
Explanation of cannabinoids
Cannabigerol (CBG), cannabichromene (CBC) and cannabinol (CBN) are some of the other cannabinoids that can be found in the cannabis plant. Each of these cannabinoids has its own special properties and possible medicinal uses.
Cannabinoids can be taken in many different ways, such as smoking or vaporizing dried cannabis flowers, eating foods that contain cannabis, or using medications, oils, and topicals that contain concentrated cannabinoids.
Although there is still much to learn about the benefits and possible risks of using cannabinoids, studies show that they have therapeutic potential for a wide range of medical conditions, such as chronic pain, anxiety, epilepsy and cancer.
What are the beneficial effects?
Even so, CBG oil will have an effect on the brain. Just like CBD, it has the ability to make people feel less anxious and may even help with depression. This may be the case because it appears to slow down the absorption rate of the chemical GABA in the body. According to the results of a study done in 2009, this effect will be stronger in mice than CBD or THC.
Cannabigrol, which does not make people feel high like THC, can be used to treat a wide variety of ailments. Cannabigerol is an antioxidant, meaning it prevents the body from producing dangerous free radicals. It seems that the fact that CBG can reduce reactive stress is what makes it possible to stop the inflammation. Everyone knows it can help reduce inflammation in the intestines, including inflammation caused by Crohn’s disease.
CBG has long been known to reduce pressure in the eyes of people with glaucoma. However, careful research with rats shows that CBG can also make people feel hungrier.
Additional benefits of Cannabigerol
It sounds hard to understand, but this method can explain some effects of CBG. including a slight drop in blood pressure. Researchers have also found that it helps with skin problems. It slows the growth of skin cells and can be used to treat psoriasis. It also helps stop allergic reactions that cause swelling and redness of the skin. psoriasis. It also helps stop allergic reactions that cause swelling and redness of the skin.
IBD stands for inflammatory bowel disease.
With inflammatory bowel disease, the bowel remains inflamed for a long time. It affects millions of people all over the world and cannot be cured.
In 2013, CBG was tested on animals with inflammatory bowel disease, and the results showed that it helped.
The researchers induced colitis in mice in a manner similar to what happens with IBD, and then gave the mice CBG. Nitric oxide and stimulation were found to be reduced by CBG. It also stopped the generation of reactive oxygen species (ROS) in the gut. They concluded that cannabigrol should be tested in people with IBD in a clinical setting.
glaucoma
In an animal study, researchers found that this cannabinoid may help treat glaucoma.
When researchers gave CBG to cats with glaucoma, eye pressure decreased and aqueous humor output increased. Aqueous humor is a fluid produced by the eye that maintains stable eye pressure and nourishes the eye.
Huntington’s disease
Nerve cells in the brain break down due to Huntington’s disease. In a 2015 study, researchers looked at how CBG and other cannabinoids might help neurons in mice with an artificial version of Huntington’s disease. It could be seen that CBG worked as a neuroprotectant, preventing the nerve cells in the brain from being damaged. It also corrected movement problems and protected striatal neurons from the damage caused by 3-nitropropionic acid.4
antibacterial properties
מחקר משנת 2020 על הפוטנציאל האנטיביוטי של קנאביס מצא שקנביגרול הורג חיידקים, במיוחד צורות עמידות לתרופות של Staphylococcus aureus (MRSA), הגורם לזיהומי staph.5
מנסה לעצור תאי סרטן
במחקר משנת 2014 על חולדות עם סרטן המעי הגס, CBG הראה פוטנציאל בחסימת הקולטנים הגורמים לצמיחת תאי סרטן ולהאט את צמיחתם של תאי סרטן המעי הגס. המומחים אמרו שניתן להשתמש ב-CBG לטיפול בסרטן המעי הגס ולמנוע ממנו לקרות.6
תופעות הלוואי של CBG
בסקר הגדול הראשון של אנשים שהשתמשו ב-CBG כדי לעזור עם דברים כמו נדודי שינה , כאבים כרוניים, דיכאון וחרדה, אנשים אמרו שזה גרם להם לצמא, עייף, רעב ועיניים יבשות. חלק מהאנשים אמרו שזה עובד טוב יותר מתרופות מסורתיות, שחלקן עלולות לגרום לתופעות לוואי חמורות ולהתמכרות .
יותר ויותר מחקרים נעשים על תופעות הלוואי האפשריות ואינטראקציות תרופתיות של CBG וקנבינואידים אחרים, אך עדיין לא נעשה מספיק כדי לומר בוודאות מה עשויות להיות תופעות הלוואי והאינטראקציות התרופתיות של קנאביגרול.
CBG vs. CBD
It is very similar to CBD in many ways:
Both work on the body’s own cannabinoid system.
They are not psychoactive, which means they don’t make you feel “hi”.
They can prevent THC from making you feel “high”.
CBD and CBG are very different in many ways, but one of the biggest is that most cannabis plants only have about 1% CBG but up to 25% CBD.
CBG and the endocannabinoid system do not work in the same way as CBD. It binds directly to CB1 and CB2 receptors, which can help the body get the most of its benefits.
